منابع مشابه
Observations on foetal haemoglobin.
Foetal haemoglobin exhibits a much greater resistance towards alkaline denaturation than does adult haemoglobin, thus constituting an important distinction between the two types of haemoglobin. The phenomenon was first described by Korber (1866), observed again by Kruger (1887-88), and subsequently studied in more detail by Bischoff (1926), Haurowitz (1929, 1930), and Brinkman, Wildschut and Wi...
متن کاملObservations on the high foetal haemoglobin gene and its interaction with the thalassaemia gene.
A family of mixed Indian-Portuguese ancestry is reported in which there is a hereditary persistence of foetal haemoglobin and beta-chain thalassaemia. The propositus, a 17-year-old boy, was found to have a mild haemolytic anaemia characterized by slight splenomegaly, microcytosis, numerous target cells, decreased osmotic fragility, a very high level of foetal haemoglobin (75%), and normal haemo...
متن کاملFoetal Haemoglobin, Erythrocytes Containing Foetal Haemoglobin, and Hematological Features in Congolese Patients with Sickle Cell Anaemia
High HbF levels and F cells are correlated with reduced morbidity and mortality in sickle cell disease (SCD). This paper was designed to determine the HbF and F cells levels in Congolese sickle cell anemia (SCA) patients in order to determine their impact on the expression of SCD. Population and Method. HbF levels were measured in 89 SCA patients (mean age 11.4 yrs) using a standard HPLC method...
متن کاملAmnioscopy and foetal blood sampling: observations on foetal acidosis.
Amnioscopy is available as an out-patient procedure, whenever hazards threaten the life of the foetus during late pregnancy. An endoscope-the amnioscope-is passed into the cervical canal so that the amniotic fluid can be inspected through the intact forewaters. Amniotic fluid which is clear, or milky from emulsification of vernix, indicates that conditions within the uterus are normal. Green or...
متن کاملCysteine - Cystine of Foetal - Human Haemoglobin
Sodium cyanide samples which gave different colour yields with a given amount of uric acid were assayed for total cyanide and titratable alkalinity, but little consistent agreement was obtained. One commercial grade giving a low colour yield had a low assay and revealed traces of iron on analysis, the latter in the ferric form considerably reduces the colour yield of uric acid. Changes in alkal...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1953
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.28.137.38